Friday, February 1, 2019

How a Canadian Pediatrician Revolutionized Prescription Safety


Cambridge Therapeutics Chairman John Klein and his team aim to provide physicians and their patients with high-quality, innovative, easy-to-manage prescription drug packaging that helps to increase patient compliance with any prescription drug regimen. A New Jersey-based company founded by John Klein in 2011, Cambridge Therapeutics puts the same level of care into ensuring that its packaging meets all applicable standards for child-resistance and safety.

Cambridge Therapeutics and its peers’ focus on ensuring safety and developing packaging that keeps prescription medications out of the hands of children has a history that extends back many decades.

In 1967, a Canadian physician, Dr. Henri Breault, patented his Palm-n-Turn prescription bottle lid. Dr. Breault began his work on the design after the tragic deaths of some 100 Canadian children every year due to accidental poisonings. As chief of pediatrics in a poison-control center at the Hotel Dieu Hospital, he had handled numerous cases in which he had to pump children’s stomachs to save their lives.

Dr. Breault’s lid is credited for a 25 percent lowering of the rate of accidental poisonings of children in the province of Ontario. Other Canadian provinces adopted it, and the United States established regulations in 1970 that required such child-resistant designs on some prescription medications. Worldwide adoption of the design led to some governments’ additional requirements that dangerous home products such as bleach also be packaged in child-resistant containers.

Dr. Breault died in 1983, but his impact on child safety has been compared to that of Jonas Salk on fighting polio.

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